A COMPARISON OF SOFOSBUVIR/VELPATASVIR AND GLECAPREVIR/PIBRENTASVIR FOR THE TREATMENT OF HEPATITIS C INFECTION AMONG PEOPLE WHO INJECT DRUGS

A comparison of sofosbuvir/velpatasvir and glecaprevir/pibrentasvir for the treatment of hepatitis C infection among people who inject drugs

Background: To eliminate hepatitis C (HCV) infection as a public health concern by 2030, there is a need to develop comprehensive programs among key populations such as people who use drugs (PWUD).Two highly effective regimens are available for initial therapy: glecaprevir/pibrentasvir (G/P) given as 3 tablets/day for 8 weeks and sofosbuvir/velpata

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Exon Array Analysis using re-defined probe sets results in reliable identification of alternatively spliced genes in non-small cell lung cancer

Abstract Background Treatment of non-small cell lung cancer with novel targeted therapies is a major unmet clinical need.Alternative splicing is a mechanism which generates diverse protein products and is of functional relevance in cancer.Results In this study, a genome-wide analysis of the alteration of splicing patterns between lung cancer and no

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